

Several words about Colchicine (Colcrys) pills anyone should know:
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Renal dosage Adjustments. Gout Flares: Mild (CrCl 50 to 80 mL/min) to moderate (CrCl 30 to 50 mL/min) renal impairment: No dose adjustment required, but patients should be monitored closely for adverse effects. Severe (CrCl less than 30 mL/min) renal impairment: No dose adjustment required, but a treatment course should not be repeated more than once every 2 weeks. For patients requiring repeated courses, consideration should be given to alternate therapy.
Patients with renal or liver impairment should not be given Colchicine in conjunction with P-gp or strong CYP450 3A4 inhibitors. In these patients, life-threatening and fatal Colchicine (Colcrys) toxicity has been reported with Colchicine taken in therapeutic doses.
Colchicine Dermatologic side effects have included urticaria, alopecia after intoxication or long-term usage, toxic epidermal necrolysis with concomitant ethanol use, fixed drug eruption, dermatitis, and purpura.
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And here are a few reviews about Colchicine (Colcrys) medicine from some people:
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Colchicine (Colcrys) for Gout, Acute: Gout is so painful. After first doses of Colchicine had immediate relief. I had fallen on my knee and was being treated for osteoarthritis with no relief. Went to arthritis doctor who told me it was gout in my knee. Went on Colcyrs and I can walk again.
It helps with the joint pain and mouth sores a bit. I get the sores less since I started treatment. I was suppose to take it twice a day but it made me quite ill.
I only use it PRN when Im having a flare up and it really seems to help. I also use it with a steroid cream and it makes it work even better!
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Also if you're not sick of reading - here are a few interesting words about health from some well known people:
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Lou Gramm: Five years ago we were working on a new album when my health began failing.
Danish Proverb: Fresh air impoverishes the doctor.
Dick York: I took pain pills to get to sleep because I didn't want to go to work the next day exhausted.
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And here we have some more facts about Colchicine (Colcrys) tablets in general:
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Dialysis. Familial Mediterranean Fever: The total recommended starting dose should be 0.3 mg/day. Dosing may be increased with close monitoring. Any increase in dosage should be done with adequate monitoring of the patient for adverse effects.
Liver dose Adjustments. Gout Flares: Mild to moderate hepatic impairment: No dosage adjustment required, but patients should be monitored closely for adverse effects. Severe hepatic impairment: No dosage adjustment required, but a treatment course should not be repeated more than once every 2 weeks. For patients requiring repeated courses, consideration should be given to alternate therapy.
Usual Adult dose for Fibromatosis - Initial: 0.6 to 1.2 mg orally once a day each day for the first 1 to 2 weeks. Maintenance: 0.6 to 1.2 mg orally once a day 1 to 2 times per week is often used to prevent recurrence of fibromatosis.
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And of course some more feedbacks about Colchicine tabs from different patients:
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Colchicine for Behcet's Disease: Been using Colchicine for over 20 years. No noticeable side effects but do get my bloods checked annually. Only problem was when returned to using it after a two year break. Some diarrhea at first but this stopped after a few weeks once body built up tolerance to drug.
I only take it when I feel an impending attack, and it is amazing. It does cause some diahrrea after 3 days of treatment, but is well worth it, instead of enduring the excruciating pain associated with gout attack. A magic pill indeed.
Really helps knock down the acute attacks of gout. health care professional says as soon as I start getting sick is time to stop taking it.
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