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Some facts about Colchicine tabs in general:

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Familial Mediterranean fever (FMF) in patients taking protease inhibitors: FDA recommends a maximum daily dose of Colchicine of 0.6 mg (may be given as 0.3 mg 2 times a day). For patients taking fosamprenavir without ritonavir, the maximum daily dosage of Colchicine is recommended to be no more than 1.2 mg (may be given as 0.6 mg 2 times a day).

Renal dose Adjustments. Familial Mediterranean Fever: Mild (CrCl 50 to 80 mL/min) to moderate (CrCl 30 to 50 mL/min) renal impairment: No dosage adjustment required, but patients should be monitored closely for adverse effects. dosage reduction may be necessary. Severe (CrCl less than 30 mL/min) renal impairment: Dosage should be started at 0.3 mg/day; any increase in dosage should be done with adequate monitoring of the patient for adverse effects. In patients with renal impairment who are taking protease inhibitors for the treatment of HIV-1 infection, the FDA has recommended against the coadministration of Colchicine (Colcrys).

Patients with hepatic or renal impairment: For the prevention or treatment of gout flares, or for FMF, FDA has recommended against the coadministration of Colchicine (Colcrys) with protease inhibitors.

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And here are a few reviews about Colchicine tablets from various patients:

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I have FMF and have been on Colchicine (Colcrys) for over 4 years now and its a miracle pill. I don't know what I would do without it. It has given me NO side effects! Very inexpensive and easy to swallow...

I am a male 67 years old with the customary ailments of a person of this age. I have experienced the painful condition of gout in my big toes in the past 4 years or so & did not know there was some medication that would have relieved my pain. However the last time I had an attack I was forced to seek medical treatment. My doctor precribed Colchicine & to make a long story short, I had almost 90% relief within 12 hours. No side affects whatsoever. It works.

It helps with the joint pain and mouth sores a bit. I get the sores less since I started treatment. I was suppose to take it twice a day but it made me quite ill.

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Also if you're not tired of reading - here are several informative expressions about health and medications from various famous people:

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Zach Braff: I'm by no means condemning prescription medicine for mental health. I've seen it save a lot of people's lives.

Jack Osbourne: Dad was just an emotional wreck. He was drinking a lot of the time, he was smoking a lot of pot. And because he takes certain medications, the drinking was making him... you know, he wasn't even present, really.

Temple Grandin: And while we are on the subject of medication you always need to look at risk versus benefit.

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And here we have some more facts about Colchicine pills should be recalled:

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Colchicine Dermatologic side effects have included urticaria, alopecia after intoxication or long-term usage, toxic epidermal necrolysis with concomitant ethanol use, fixed drug eruption, dermatitis, and purpura.

FDA pregnancy category C. It is not known whether Colchicine (Colcrys) will harm an unborn baby. Tell your healthcare professional if you are pregnant or plan to become pregnant while using this medication. It is not known whether Colchicine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your healthcare professional if you are breast-feeding a baby.

Seek medical attention right away if any of these severe side effects occur: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fever; infection; numbness or tingling; severe diarrhea; sore throat; tiredness; unusual bleeding or bruising; weakness.

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And of course a few more reviews about Colchicine (Colcrys) tablets from different people:

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Colchicine (Colcrys) for Gout, Prophylaxis: Unusual medication, but works fast and effectively, totally removing gout symptoms.

I recently switched from generic Colchicine (Colcrys) to Colchicine, from AR Scientific, for long term treatment of Familial Mediterranean Fever. So far the Colchicine (Colcrys) has helped reduce my symptoms better than the generic Colchicine (Colcrys). The side effects so far have been the same as with Colchicine. The price is higher, but hopefully that will mean a more consistant product.

This is my 3rd and worse bout with gout. My Dr. prescribed this medication and forewarned me that it MAY cause diarahea. He suggested one 0.6 mg pill every four hours instead of every one to two hours. It took just a little longer but after taking this for 18 hours the front of my foots swelling has gone down 50% and the pain has subsided by over 75%. When this attack is over , he is starting my on Allopurinol to avoid this in the future. In short, Colchicine is a god sent medication.

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