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Several words about Colchicine (Colcrys) medicine in general:

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Renal dosage Adjustments. Familial Mediterranean Fever: Mild (CrCl 50 to 80 mL/min) to moderate (CrCl 30 to 50 mL/min) renal impairment: No dose adjustment required, but patients should be monitored closely for adverse effects. dose reduction may be necessary. Severe (CrCl less than 30 mL/min) renal impairment: Dosage should be started at 0.3 mg/day; any increase in dose should be done with adequate monitoring of the patient for adverse effects. In patients with renal impairment who are taking protease inhibitors for the treatment of HIV-1 infection, the FDA has recommended against the coadministration of Colchicine.

Renal dose Adjustments. Gout Flares: Mild (CrCl 50 to 80 mL/min) to moderate (CrCl 30 to 50 mL/min) renal impairment: No dosage adjustment required, but patients should be monitored closely for adverse effects. Severe (CrCl less than 30 mL/min) renal impairment: No dose adjustment required, but a treatment course should not be repeated more than once every 2 weeks. For patients requiring repeated courses, consideration should be given to alternate therapy.

Usual Adult dosage for Aphthous Stomatitis - Recurrent - 0.5 to 0.6 mg orally daily. The dosage may be titrated upward while the patient is observed for signs of toxicity.

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And here are several experiences about Colchicine medication from various men and women:

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While on Azathioprine my awesome Rheumatologist suggested Colchicine because my mucosal ulcerations were not going away. This worked wonders and since I have been on it have had constant dependable results. I am off the Azathioprine and on Humira but still taking Colchicine. This drug I have to say has given me the most improvement of my quality of life.

I have been suffering from gout for past 10 years. One instance the pain was so bad I had to call the on call physician. I was diagnosed with gout. I was prescribed Colchicine for the pain. The pain stopped and the swelling decreased. I now take the medication daily and have no problems. I have no complains since I have been on this medication. I'll deal with the side effects of the medication than the severe pain from the gout which is unbearable.

I do feel this works pretty steady for me.. Not really any stomach issues, just the occassional need to use the toilet often... so I time it and usually stay home when taking this. Im sure to drink lots of water.

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Also if you're not sick of reading - here are some in some way funny expressions connected with health from various widely known people:

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Hillary Clinton: You cannot have maternal health without reproductive health. And reproductive health includes contraception and family planning and access to legal, safe abortion.

Marcel Proust: Illness is the most heeded of doctors: to goodness and wisdom we only make promises; pain we obey.

Robert Evans: Buildings designed with careful attention to aesthetics arouse and enlighten their occupants and that promotes their good health.

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And here we have more words about Colchicine (Colcrys) tablets anyone should know:

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Usual Adult dose for Gout - Prophylaxis - Oral: 0.5 to 0.6 mg orally once a day for 3 to 4 days a week (less than 1 attack/year). 0.5 to 0.6 mg orally once a day (greater than 1 attack/year). Severe cases may require 1 to 1.8 mg/day.

Patients with renal or liver impairment should not be given Colchicine (Colcrys) in conjunction with P-gp or strong CYP450 3A4 inhibitors. In these patients, life-threatening and fatal Colchicine (Colcrys) toxicity has been reported with Colchicine (Colcrys) taken in therapeutic doses.

Call your health care professional at once if you have a serious side effect such as muscle pain or weakness, numbness or tingly feeling in your fingers or toes, severe vomiting or diarrhea, easy bruising or bleeding, feeling weak or tired, flu symptoms, blood in your urine, urinating less than usual or not at all, or a pale or gray appearance of your lips, tongue, or hands.

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And of course a few more testimonials about Colchicine pills from various patients:

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Colchicine (Colcrys) for Gout, Acute: I am subject to relatively frequent gout flare up, every 2-3 months or so. At the first symptoms I take one 0.5 mg of Colchicine every three hours and most of the time after 2-3 pills the pain is gone. I also take 1-2 pills of imodium to avoid the diarrhea.It works fine for me

I have FMF and have been on Colchicine (Colcrys) for over 4 years now and its a miracle pill. I don't know what I would do without it. It has given me NO side effects! Very inexpensive and easy to swallow...

I had better and faster results when I was taking the generic Colchicine (Colcrys).Colchicine is slower to react to my flareups. Taking several days to obtain relief as opposed to several hours with the generic Colchicine.

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