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Renal dosage Adjustments. Gout Flares: Mild (CrCl 50 to 80 mL/min) to moderate (CrCl 30 to 50 mL/min) renal impairment: No dose adjustment required, but patients should be monitored closely for adverse effects. Severe (CrCl less than 30 mL/min) renal impairment: No dosage adjustment required, but a treatment course should not be repeated more than once every 2 weeks. For patients requiring repeated courses, consideration should be given to alternate therapy.

Usual Adult dosage for Constipation - Chronic - 0.6 mg orally three times daily for 4 weeks. Usual Adult dosage for Sweet's Syndrome - 0.6 mg orally twice daily.

Usual Adult dosage for Fibromatosis - Initial: 0.6 to 1.2 mg orally once a day each day for the first 1 to 2 weeks. Maintenance: 0.6 to 1.2 mg orally once a day 1 to 2 times per week is often used to prevent recurrence of fibromatosis.

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And here are several feedbacks about Colchicine (Colcrys) drug from various patients:

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It helps with the joint pain and mouth sores a bit. I get the sores less since I started treatment. I was suppose to take it twice a day but it made me quite ill.

Really helps knock down the acute attacks of gout. doctor says as soon as I start getting sick is time to stop taking it.

I recently switched from generic Colchicine (Colcrys) to Colchicine, from AR Scientific, for long term treatment of Familial Mediterranean Fever. So far the Colchicine has helped reduce my symptoms better than the generic Colchicine (Colcrys). The side effects so far have been the same as with Colchicine. The price is higher, but hopefully that will mean a more consistant product.

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Also if you're not tired of reading - here are some interesting expressions about healthy life from various famous persons:

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Bob Barker: I think that age as a number is not nearly as important as health. You can be in poor health and be pretty miserable at 40 or 50. If you're in good health, you can enjoy things into your 80s.

Stephen Harper: I think first and foremost everybody should understand that Canadians are strongly committed to the system of universal health insurance, to the principle that your ability to pay does not determine your access to critical medical service.

Jim Carrey: My mother was a professional sick person; she took a lot of pain pills. There are many people like that. It's just how they are used to getting attention. I always remember she's the daughter of alcoholics who'd leave her alone at Christmas time.

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And here we have even more facts about Colchicine (Colcrys) tablets in general:

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Colchicine (Colcrys) is not a cure for gouty arthritis or Behcets syndrome, and it will not prevent these diseases from progressing. Colchicine (Colcrys) should not be used as a routine pain medication for other conditions. Colchicine may also be used for purposes not listed in this medication guide.

Patients with renal or liver impairment should not be given Colchicine in conjunction with P-gp or strong CYP450 3A4 inhibitors. In these patients, life-threatening and fatal Colchicine (Colcrys) toxicity has been reported with Colchicine (Colcrys) taken in therapeutic dosages.

Store Colchicine at 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not store in the bathroom. Keep Colchicine (Colcrys) out of the reach of children and away from pets.

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And of course some more feedbacks about Colchicine tabs from various people:

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I have taken Colchicine off and on during flares, and it seems that it has helped , but it sure makes intestinal problems. I don't want to go out anywhere while taking this medication.

I thought gout so I talked to the doctor again and she looked at it and said possible gout and Rx'ed me with Colchicine (Colcrys) for 5 days. AFTER 2 DAYS I WAS PAIN FREE!! NO PAIN IN MY FEET, SHOULDERS, ELBOWS, KNEES, HANDS, MUSCLES. ANYWHERE. I COULD RUN UP AND DOUM THE STEPS. This was a miricle to me. I have been pain free up till about 2 wks. ago. I am breaking down and giong to have the uric acid blood test. If it is gout then she will Rx allipurinol(sp)? If I dont have gout then I dont know what I do have but Colchicine (Colcrys) was my miracle drug.

Colchicine for Gout, Prophylaxis: This is a great drug for gout flareups. The problem is that the cost went from 5 cents per pill to $5.50 per pill

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